Exostosin-1 Peptide
Proteins and Peptides
- 貨號 Cat. No.
- 350499
- 規格 Size
- 0.1 mg
- 品牌 Brand
- Abbiotec
Description
Exostosin-1 (EXT1) is a glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. EXT1 is a tumor suppressor. Defects in EXT1 are the cause of multiple exostoses disorders, i.e. skeletal deformities and bone tumors.