Estradiol Saliva ELISA

Estradiol (17β-estradiol) is a sex hormone. It
represents the major estrogen in humans. Estradiol
has not only a critical impact on reproductive and
sexual functioning, but also affects other organs
including bone structure.
During the reproductive years most estradiol in
women is produced by the ovaries, smaller amounts
of estradiol are also produced by the adrenal cortex.
In men, the testes produce estradiol.
During pregnancy estrogen levels including estradiol
rise steadily towards term. Estradiol increases due to
placental production.
In adult premenopausal women, ovarian estradiol
production is stimulated by the interactions of
luteinizing hormone (LH) and follicle-stimulating
hormone (FSH) throughout the menstrual cycle.
In adult women, estradiol levels are measured in the
evaluation of fertility and menstrual irregularities, and
to monitor ovarian follicular function during induction
of ovulation
In the female, estradiol acts as a growth hormone for
tissue of the reproductive organs.
The development of secondary sexual characteristics
in women is driven by estradiol. Estradiol is involved
in man feritility.
Estradiol regulate the bone maintenance. Women
who past the menopause experience an accelerated
loss of bone mass due to a relative estrogen
deficiency.
Estradiol affects the production of multiple proteins
including lipoproteins, binding proteins, and proteins
responsible for blood clotting. Estrogens have been found to have neuroprotective
function.
Estrogen is considered an oncogene as its supports
certain cancers, notably breast cancer and cancer of
the uterine lining. In addition there are several benign
gynecologic conditions that are dependent on
estrogen such as endometriosis, leiomyomata uteri,
and uterine bleeding.