ESAT-6 Mycobacterium (11G4) Antibody

h1 class=titleESAT-6 Mycobacterium (11G4) Antibody/h1
div id=node-522 class=node ntype-antibodiesMouse Monoclonal
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h4Catalog Number/h4
pstrong250322/strong/p
h4Unit/h4
pstrong0.2 mg /strong/p
h4Format/h4
pEach vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography./p
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h4Description/h4
pESAT-6 (6-kDa early secretory antigenic target) from Mycobacterium tuberculosis H37Rv (ATCC 27294) is a secreted tubercular protein that forms a dominant target for cell-mediated immunity in the early phase of infection. The deduced amino acid sequence indicates a molecular mass of 10 kDa. It is present in M. tuberculosis, virulent strains of M. bovis, and in M. flavescens, M. kansasii, M. marinum,and M. szulgai, but not in avirulent M. bovis BCG substrains. This antibody reacts with ESAT-6 in immunoblotting after SDS-PAGE of short-term culture filtrates of M. tuberculosis and virulent strains of M. bovis. The antibody cross-reacts with MPB64 (26 kDa) from certain BCG substrains, with the A, B, and C components of the antigen 85 complex and with MPT51./p
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h4Product Citations/h4
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h4Recommended Products/h4
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h4Alternate Names/h4
p6 kDa early secretory antigenic target/p
h4Accession No./h4
pa class=accession-link target=_blank href=http://www.expasy.org/uniprot/P0A564P0A564/abr /
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h4Clonality/h4
p11 G4/p
h4Antigen/h4
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pPurified protein derivative (PPD) of tuberculin from M. tuberculosis conjugated with thimerosal N-hydroxysuccinimide ester and adsorbed to aluminum hydroxide gel (4)./p
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h4Application Notes/h4
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pProduct Cat. No. 250322 reacts with PPD, culture filtrate, cytosol and cell wall preparations from M. tuberculosis./p
pE: 1:3,200;/p
pWB: 1:500/p
pstrongReacts with/strongnbsp; :Other/p
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h4Storage/h4
pStore at 4deg;C. Product is guaranteed 6 months from the date of shipment./p
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