Erlotinib, Hydrochloride Salt
- 貨號 Cat. No.
- 1588-1000
- 規格 Size
- 1 g
Description
Alternate Name/Synonyms: CP-358774, OSI-775
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 183319-69-9
Molecular Formula: C₂₂H₂₃N₃O₄.HCl
Molecular Weight: 429.9
Purity: ≥99% by HPLC
Solubility: DMSO
Storage Temp.: -20°C
Shipping Conditions: RT
Description: Erlotinib is an inhibitor of human Epidermal growth factor receptor (EGFR) tyrosine kinase (ICâ‚…â‚€ = 2 nM) and decreases EGFR autophosphorylation in tumor cells (ICâ‚…â‚€ = 20 nM). Studies in cell lines and enzyme assays have both shown that erlotinib inhibits EGFR at concentrations significantly lower than those needed to inhibit c-src and v-abl.
Handling: Protect from light and moisture