ERK1/2 Antibody

h1 class=titleERK1/2 Antibody/h1
div id=node-1293 class=node ntype-antibodiesMouse Polyclonal
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h4Catalog Number/h4
pstrong250635/strong/p
h4Unit/h4
pstrong0.1 mg/strong/p
h4Format/h4
pEach vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography./p
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h4Description/h4
pThe activation of signal transduction pathways by growth factors, hormones and neurotransmitters is mediated through two closely related MAP kinases, p44 and p42 encoded by ERK1 and ERK2 respectively. Both kinases are regulated by dual specific phosphorylation on tyrosine and threonine in response to insulin and NGF. ERK1 and ERK2 are involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK1./p
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h4Product Citations/h4
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h4Recommended Products/h4
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h4Alternate Names/h4
pERK-1; Mitogen-activated protein kinase 3; Extracellular signal-regulated kinase 1; Insulin-stimulated MAP2 kinase; MAP kinase 1; MAPK1; p44-ERK1; ERT2; p44-MAPK; Microtubule-associated protein 2 kinase; MAPK3; ERK1; PRKM3; and for ERK-2; Mitogen-activated protein kinase 1; Extracellular signal-regulated kinase 2; Mitogen-activated protein kinase 2; MAP kinase 2; MAPK2; p42-MAPK; ERT1; MAPK1; ERK2; PRKM1; PRKM2/p
h4Accession No./h4
pa class=accession-link target=_blank href=http://www.expasy.org/uniprot/P27361P27361/abr /
a class=accession-link target=_blank href=http://www.expasy.org/uniprot/P28482P28482/abr /
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h4Clonality/h4
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h4Antigen/h4
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pKLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human ERK1/2./p
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h4Application Notes/h4
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pE: 1:500-1:1,000/p
pWB: 1:200-1:500/p
pIHC: 1:200-1:500/p
pstrongReacts with/strongnbsp; :H/p
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h4Storage/h4
pStore at -20deg;C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment./p
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