Ephrin-A4 (164)Antibody

貨號 Cat. No.
BS1109
規格 Size
100μg
品牌 Brand
Bioworld

Description

stock



Host: Rabbit


Reactivity: Human,Mouse


 



Product


1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.




Purification & Purity


The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).




Specificity


Ephrin-A4 (164) antibody detects endogenous levels of Ephrin-A4 protein.




Applications (Recommended Dilutions)


WB: 1:500~1:1000






Western Blot(WB)



Western blot (WB) analysis of Ephrin-A4 (164) antibody in extracts from HepG2 cells.





Storage&Stability


Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.




Background


Ephrin A4 is also known as LERK4 or ELF4. Ephrin A4 binds EphA2, EphA3, EphA4, EphA5, EphA6, EphA7, and EphB1. To date, at least 14 members of the Eph receptor family and a family of 8 ligands have been identified. Ligands of Eph family receptors are structurally related membrane bound proteins that can be subdivided into two major subclasses: ephrin A and ephrin B. Ligands in the ephrin A subclass, including the prototype family member ephrin A1 (B61), are membrane associated through glycosylphosphatidyl inositollinkages; whereas ephrin B subclass consists of ligands with transmembrane domains. The general role of the Eph family is in mediating repulsive cell to cell interaction, as suggested by studies of axonal guidance and neural crest cell migration.


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