Enzastaurin (LY317615)
- 貨號 Cat. No.
- 1619-1
- 規格 Size
- 1 mg
Description
Alternate Name/Synonyms: LY317615, LY-317615, D04014
Appearance: Red-Orange Solid
Formulation: N/A
CAS Number: 170364-57-5
Molecular Formula: C₃₂H₂₉N₅O₂
Molecular Weight: 515.61
Purity: ≥99% by HPLC
Solubility: DMSO (5 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: RT
Description: Enzastaurin (Enz) is a potent and selective inhibitor of PKCβ with antiproliferative activity (ICâ‚…â‚€= ~6 nM). Enz suppresses VEGF-induced angiogenesis in the rat corneal micropocket assay, decreases microvessel density, and prevents VEGF secretion from human tumor cell xenografts in nude mice. Prolonged courses of Enz increase chemotherapy or radiation tumor growth delay of glioma, breast, and small cell lung cancer xenografts.
Handling: Protect from air and light