EBNA-3 Antibody

Epstein-Barr nuclear antigen 3 (EBNA-3) plays an essential role for activation and immortalization of human B cells. This family contains EBNA-3A, 3B and 3C that are latent infection nuclear proteins important for the immune response to Epstein-Barr virus (EBV) infection. EBNA-3 represses transcription of viral promoters TP1 and Cp through interaction with host RBPJ, and inhibits EBNA2-mediated activation of these promoters. This antibody binds to EBNA-3A.