E-cadherin Peptide

h1 class=titleE-cadherin Peptide/h1
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h4Catalog Number/h4
pstrong350496/strong/p
h4Unit/h4
pstrong0.1 mg/strong/p
h4Price/h4
pstrong$50.00/strong/p
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h4Description/h4
pCadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. E-cadherin (CDH1) is involved in mechanisms regulating cell-cell adhesion, mobility and proliferation of epithelial cells. CDH1 has a potent invasive suppressor role. CDH1 binds to integrin alpha-E/beta-7. Defects in CDH1 are the cause of gastric, endometrial, breast, ovary and thyroid cancers. This antibody may cross-react with cadherin-2, 3 and 4./p
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h4Format/h4
pnbsp;/p
pEach vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect./p
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h4Data and Images/h4
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h4Product Citations/h4
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h4Recommended Products/h4
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a href=http://abbiotec.com/antibodies/e-cadherin-antibody200134 E-cadherin Antibody/abr /
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h4Alternate Names/h4
pEpithelial cadherin; Uvomorulin; Cadherin-1; CAM 120/80; CD324 antigen; CDH1; CDHE; UVO/p
h4Accession No./h4
pa class=accession-link href=http://www.expasy.ch/uniprot/P12830 target=_blankP12830/abr /
a class=accession-link href=http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=proteinamp;id=4757960 target=_blankNP_004351/abr /
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h4MW/h4
p2121.1 g/mol/p
h4Sequence/h4
pThe synthetic peptide used to raise the antibody Cat. No. 200134 is selected from a sequence within the C-term region of human E-cadherin. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended./p
h4Composition/h4
pnbsp;/p
pC89H125N25O34S1/p
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h4Purity/h4
pPurity gt; 80% by HPLC/p
h4Solubility/h4
pDistilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile./p
h4Storage/h4
pStore at -20deg;C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20deg;C./p
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