E-cadherin (G2) Antibody

貨號 Cat. No.

BS1097

規格 Size

100μg

品牌 Brand

Bioworld

Description

stock

Host: Rabbit

Reactivity: Human

 

Product

1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.

Purification & Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity

E-cadherin(G2) antibody detects endogenous levels of E-cadherin protein.

Applications (Recommended Dilutions)

WB: 1:500~1:1000 IF: 1:50~1:200 IHC: 1:50~1:200

Western Blot(WB)

Western blot (WB) analysis of E-cadherin (G2) antibody in extracts from 293 cells.

Immunohistochemistry (IHC)

Immunohistochemistry (IHC) analyzes of E-cadherin (G2) antibody in paraffin-embedded human breast carcinoma tissue.

Storage&Stability

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Background

Cadherins are members of a multigene family of single chain glycoprotein receptors mediating calcium dependent cell-cell adhesion. They play an important role in the growth and development of cells via the mechanisms of control of tissue architecture and the maintenance of tissue integrity. Cadherins are expressed in a tissue specific manner and and are required for assembly of cells into solid tissue. Individual cadherin molecules are known to co-operate with each other to form a linear cell adhesion zipper. In adhesion junctions cadherins are bound to beta and gamma catenins which in turn bind to alpha catenin, an actin binding protein. Cadherins play an important part in tumor invasion and metastasis.

詢價 / 洽詢此產品