DR4 Antibody
- 貨號 Cat. No.
- 3061A-100
- 規格 Size
- 100 µg
Description
pfont size=2strongAntibody Target :/strongDR4/TRAIL-R1 /font/p
pbHost: /bRabbit/p
pbAntibody Type: /bPolyclonal/p
pbIsotype: /bRabbit IgG/p
pbAntibody Form: /bAffinity Purified Antibody/p
pbImmunogen Sequence: /bSynthetic peptide corresponding to residues surrounding amino acids 454 of human DR4/p
pbAccession#: /bEAW63636.1/p
pbGene ID: /b8797/p
pbAppearance: /bColorless liquid/p
pbConcentration: /b0.5 mg/ml/p
pbFormulation: /b100 micro;g (0.5 mg/ml) affinity purified rabbit anti-DR4 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal./p
pbPurification: /bAffinity purified/p
pbSpecies Reactivity: /bms/p
pbApplication: /bWB/p
pbApplication amp; Usage: /bWestern blot analysis (0.5-4 micro;g/ml) and immunofluorescence. However, the optimal conditions should be determined individually. The antibody detects a 57 kDa mouse DR4 in Western blot analysis./p
pbStorage Temp.: /b-20 deg;C/p
pbShipping : /bgel pack/p
pbShelf Life: /b12 months/p
pbHandling: /bThe antibody solution should be gently mixed before use./p
pbBrief Background Descriptions: /bApoptosis can be induced by certain cytokines including TNF and Fas Ligand of the TNF super-family through their death domain (DD) containing receptors, TNFR1 and Fas. A member of the TNF receptor family was recently identified and designated DR4 (death receptor 4) and TRAIL-R1. The ligand for this novel death receptor has been identified and termed TRAIL. DR4 is expressed in most of the human tissues including spleen, peripheral blood leukocytes (PBLs), small intestine and thymus. Like TNFR1, Fas and DR3, DR4 mediates apoptosis and NFkB activation in many tissues and cells./p
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pbHost: /bRabbit/p
pbAntibody Type: /bPolyclonal/p
pbIsotype: /bRabbit IgG/p
pbAntibody Form: /bAffinity Purified Antibody/p
pbImmunogen Sequence: /bSynthetic peptide corresponding to residues surrounding amino acids 454 of human DR4/p
pbAccession#: /bEAW63636.1/p
pbGene ID: /b8797/p
pbAppearance: /bColorless liquid/p
pbConcentration: /b0.5 mg/ml/p
pbFormulation: /b100 micro;g (0.5 mg/ml) affinity purified rabbit anti-DR4 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal./p
pbPurification: /bAffinity purified/p
pbSpecies Reactivity: /bms/p
pbApplication: /bWB/p
pbApplication amp; Usage: /bWestern blot analysis (0.5-4 micro;g/ml) and immunofluorescence. However, the optimal conditions should be determined individually. The antibody detects a 57 kDa mouse DR4 in Western blot analysis./p
pbStorage Temp.: /b-20 deg;C/p
pbShipping : /bgel pack/p
pbShelf Life: /b12 months/p
pbHandling: /bThe antibody solution should be gently mixed before use./p
pbBrief Background Descriptions: /bApoptosis can be induced by certain cytokines including TNF and Fas Ligand of the TNF super-family through their death domain (DD) containing receptors, TNFR1 and Fas. A member of the TNF receptor family was recently identified and designated DR4 (death receptor 4) and TRAIL-R1. The ligand for this novel death receptor has been identified and termed TRAIL. DR4 is expressed in most of the human tissues including spleen, peripheral blood leukocytes (PBLs), small intestine and thymus. Like TNFR1, Fas and DR3, DR4 mediates apoptosis and NFkB activation in many tissues and cells./p
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