Doxazosin Mesylate

貨號 Cat. No.: S1324
規格 Size: 10mM/1mLã€50mg
品牌 Brand: Selleckchem

Description

Doxazosin Mesylate

Catalog No.S13241 Product Citations

Doxazosin Mesylate is an alpha-1 adrenergic receptor blocker.

Size

Price

Stock

Quantity

10mM/1mLIn DMSO	USD 163	In stock	0 1 2 3 4 5 6 7 8 9 10
50mg	USD 122	In stock	0 1 2 3 4 5 6 7 8 9 10

Distributor Tel: +886-2-2827-1197jimmy@new.abscience.com.tw

Biological Activity

Doxazosin mesylate , a quinazoline compound, is an alpha-1 adrenergic receptor blocker used to treat high blood pressure and benign prostatic hyperplasia. It inhibits the binding of norepinephrine to the alpha-1 receptors on the membrane of vascular smooth muscle cells. The primary effect of this inhibition is relaxed vascular smooth muscle tone (vasodilation), which decreases peripheral vascular resistance, leading to decreased blood pressure. [1]

Clinical Trial Information( data from http://clinicaltrials.gov)

NCT Number	Recruitment	Conditions	Sponsor /Collaborators	Phases
NCT01953432	Not yet recruiting	Cocaine Dependence	Department of Veterans Affairs\|Baylor College of Medicine	Phase 2
NCT01959022	Recruiting	Stress Disorders, Post-Traumatic	San Francisco Veterans Administration Medical Center\|Department of Defense\|Northern California Institute of Research and Education	Phase 4
NCT01946035	Recruiting	Allergic Rhinitis	University of Dundee	Phase 4
NCT01730846	Recruiting	Smoking	Yale University\|National Institute on Drug Abuse (NIDA)	Phase 2
NCT01678313	Recruiting	Benign Prostatic Hyperplasia	Buddhist Tzu Chi General Hospital	Phase 2

Chemical Information

Download Doxazosin Mesylate SDF

Molecular Weight (MW)	547.58
Formula	C23H25N5O5.CH4O3S
CAS No.	77883-43-3

Storage	3 years -20â„ƒPowder
Storage	6 months-80â„ƒin DMSO
Syonnyms	Cardura, Carduran

Solubility (25°C) *	In vitro	DMSO	15 mg/mL (27 mM)
		Water	<1 mg/mL (<1 mM)
		Ethanol	<1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.