Dorsomorphin

Alternate Name/Synonyms: 6-[4-(2-Piperidin-1-yl)-ethoxy)-phenyl)]-3-pyridin-4-yl- pyrazolo[1,5-a]-pyrimidine; Compound C

Appearance: Light yellow solid

Formulation: N/A

CAS Number: 866405-64-3

Molecular Formula: Câ‚‚â‚„Hâ‚‚â‚…Nâ‚…O

Molecular Weight: 399.49

Purity: ≥98% by HPLC

Solubility: DMSO (>5 mg/ml)

Storage Temp.: +4C

Shipping Conditions: RT

Description: Cell-permeable. A potent, selective , reversible and ATP-competitive inhibitor of AMP-activated protein kinase (AMPK) (Ki = 109 nM in the presence of 5 µM ATP and no AMP). Does not affect the activity on several structurally related kinases including JAK3, PKA, PKCθ, SYK and ZAPK. Also inhibits bone morphogenic protein (BMP) type I receptors (ALK2, ALK3 and ALK6).

Handling: Protect from air and light