DOK Polyclonal Antibody
- 貨號 Cat. No.
- 3184-100
- 規格 Size
- 100 ug
Description
pimg src=http://www.biovision.com/Merchant2/graphics/00000001/antibody-stock-miva.jpg alt= /nbsp;/p
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pbFORMULATION: /b100 ug (0.2 mg/ml) affinity-purified rabbit anti-p62DOK polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% sodium azide./p
pbSTORAGE CONDITIONS: /bStore at -20oC. For long term storage, aliquot and freeze at -70oC. Avoid repeated freeze/defrost cycles./p
pbSPECIES REACTIVITY: /bhuman/p
pbBACKGROUND DESCRIPTION: /bSignals from most growth factors and cytokines are transduced by tyrosine kinases. Activated tyrosine kinases phosphorylate their substrates, which mediate the cellular response to extracellular stimuli. A long-sought major substrate termed p62DOK (downstream of tyrosine kinase) for many tyrosine kinases (including c-kit, v-abl, v-Fps, v-Src, v-Fms, and activated EGF, PDGF, IGF, VEGF and insulin receptors) was identified recently from human and mouse by several groups. Upon phosphorylation, p62DOK forms a complex with the ras GTPase-activating protein (RasGAP). p62DOK represents a new family with very recently identified p56DOK./p
pbAPPLICATION AND USAGE: /bThe antibody can be used for Western blot (at 1-2 ug/ml). However, the optimal conditions should be determined individually./p
pbSPECIFICITY: /bThe antibody detects 62 kDa human DOK. NOTE:/p
pbFOR RESEARCH USE ONLY! Not to be used in human. /b/p
pfont size=2 /font/p
pbFORMULATION: /b100 ug (0.2 mg/ml) affinity-purified rabbit anti-p62DOK polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% sodium azide./p
pbSTORAGE CONDITIONS: /bStore at -20oC. For long term storage, aliquot and freeze at -70oC. Avoid repeated freeze/defrost cycles./p
pbSPECIES REACTIVITY: /bhuman/p
pbBACKGROUND DESCRIPTION: /bSignals from most growth factors and cytokines are transduced by tyrosine kinases. Activated tyrosine kinases phosphorylate their substrates, which mediate the cellular response to extracellular stimuli. A long-sought major substrate termed p62DOK (downstream of tyrosine kinase) for many tyrosine kinases (including c-kit, v-abl, v-Fps, v-Src, v-Fms, and activated EGF, PDGF, IGF, VEGF and insulin receptors) was identified recently from human and mouse by several groups. Upon phosphorylation, p62DOK forms a complex with the ras GTPase-activating protein (RasGAP). p62DOK represents a new family with very recently identified p56DOK./p
pbAPPLICATION AND USAGE: /bThe antibody can be used for Western blot (at 1-2 ug/ml). However, the optimal conditions should be determined individually./p
pbSPECIFICITY: /bThe antibody detects 62 kDa human DOK. NOTE:/p
pbFOR RESEARCH USE ONLY! Not to be used in human. /b/p