DKK-1 (Dickkopf-1) ELISA

pDKK-1 (Dickkopf-1) ELISA/p
pimg alt=For Research Use Only align=absMiddle src=http://www.alpco.com/img/ruo.gif / For Research Use Only/p
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div class=prod_specbFormat:/b/div
div class=prod_spec_infoELISA / EIA/div
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div class=prod_specSample Type:/div
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div class=prod_specbSample Size:/b/div
div class=prod_spec_info15 micro;l/div
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div class=prod_specbSize:/b/div
div class=prod_spec_info96 wells/div
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div class=prod_specbRange:/b/div
div class=prod_spec_info3.125 - 50 pmol/L/div
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div class=prod_specbSensitivity:/b/div
div class=prod_spec_info0.38 pmol/l/div
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pbSummary:/b/p
The DKK-1 ELISA is an enzyme immunoassay intended for the quantitative determination of human DKK-1 in Serum. Dickkopf-1 (DKK-1) is a 28,672 Da secreted protein that acts as soluble inhibitor of the wnt signalling pathway. This pathway involves lipid modied glycoproteins that activate cell surface receptor-mediated signal transduction to regulate cellular activities such as cell fate, proliferation, migration, polarity and gene expression. DKK-1 is also involved in the regulation of bone metabolism as it effects osteoblast differentiation and in the regulation of tumorigenic activity. Possible indications include osteoarthritis, osteoporosis, colon carcinomas, multiple myeloma and breast cancer metastasis to bone./div
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