Diamineoxidase (DAO) (IDK® DAO) ELISA

Diamine oxidase (DAO) is a body‘s own enzyme that metabolises histamine. Although
DAO is found practically in the whole body, the most important site of its
action is the intestine. The enzymatic activity of DAO determines the histamine
degradation speed. In the case of DAO deficiency or inhibition, incorporated or endogenous
histamine cannot be degraded quickly enough, and the symptoms of
histamine intolerance are presented. Millions of people suffer from gastrointestinal
problems, migraine, irritations of nasal mucosa and other allergy-like symptoms after
consumption of certain nutrients. Too much histamine in the body can be the reason
for this wide range of symptoms.
The determination of DAO serum concentration (K 8500) combined with the determination
of DAO activity (K 8220 DAO REA) is a suitable marker for the differential
diagnosis of histamine intolerance and associated symptoms.
Our IDK® DAO ELISA kit is intended for determination of the diamine oxidase (DAO)
concentration in serum.