Diamineoxidase (DAO) (³H-Nuclid) REA (100 Tests)

Diamine oxidase (DAO) is a body‘s own enzyme that metabolizes histamine. Although DAO
is found practically in the whole body, the most important site of its action is the intestine. The
enzymatic activity of DAO determines the histamine degradation speed. In the case of DAO
deficiency or inhibition, incorporated or endogenous histamine cannot be degraded quickly
enough, and the symptoms of histamine intolerance are presented. Millions of people suffer
from gastrointestinal problems, migraine, irritations of nasal mucosa and other allergy-like
symptoms after consumption of certain nutrients. Too much histamine in the body can be the
reason for this wide range of symptoms. Another possibility for reduced DAO function could
be the intake of activity-inhibiting substances, such as alcohol or medication.
Histamine induced food intolerance is not IgE-mediated. Determination of the DAO activity in
serum or plasma is a suitable marker for diagnosis of histamine intolerance and the associated
symptoms.
With our easy-to-use, reliable and standardised test kit it is possible to quantify the biological
activity of DAO in the circulation. Only 100µl of serum is needed for the test, results are available
within 3 hours.