DFF45 Antibody
- 貨號 Cat. No.
- 3048-100
- 規格 Size
- 100 µg
Description
pfont size=2strongAntibody Target :/strongDFF45 /font/p
pstrongHost: Rabbit /strong/p
pstrongAntibody Type: Polyclonal /strong/p
pstrongIsotype: Rabbit IgG /strong/p
pstrongAntibody Form: Affinity Purified Antibody /strong/p
pstrongImmunogen Sequence: Synthetic peptide mapping to the N-terminus of mouse DFF45 /strong/p
pstrongAccession#: AAH58213 /strong/p
pstrongGene ID: 13347 /strong/p
pstrongAppearance: Colorless liquid /strong/p
pstrongConcentration: 0.2 mg/ml /strong/p
pstrongFormulation: 100 micro;g (0.2 mg/ml) immunoaffinity purified rabbit DFF45 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal. /strong/p
pstrongPurification: Affinity purified /strong/p
pstrongSpecies Reactivity: ms/rt /strong/p
pstrongApplication: WB /strong/p
pstrongApplication amp; Usage: Western blotting (0.5-4 micro;g/ml). However, the optimal conditions should be determined individually. The antibody detects the 45 kDa and 28 kDa proteins, corresponding to the apparent molecular weight of DFF45/ICADL, and ICADS in immunoblots. /strong/p
pstrongStorage Temp.: -20 deg;C /strong/p
pstrongShipping : gel pack /strong/p
pstrongShelf Life: 12 months /strong/p
pstrongHandling: The antibody solution should be gently mixed before use. /strong/p
pstrongBrief Background Descriptions: Apoptosis occurs during normal cellular development and involves dramatic changes in cellular structure. Disruption of apoptosis may contribute to cancer as well as many other types of diseases. Recently, a human DNA fragmentation factor (DFF45) was identified. DFF is composed of two subunts: DFF40 and DFF45. Cleavage of DFF45, which is mediated by caspase-3, leads to DFF40rsquo;s activation as a nuclease. Activation of DFF40 can lead to DNA fragmentation, a hallmark of apoptosis. /strong/p
pstrongHost: Rabbit /strong/p
pstrongAntibody Type: Polyclonal /strong/p
pstrongIsotype: Rabbit IgG /strong/p
pstrongAntibody Form: Affinity Purified Antibody /strong/p
pstrongImmunogen Sequence: Synthetic peptide mapping to the N-terminus of mouse DFF45 /strong/p
pstrongAccession#: AAH58213 /strong/p
pstrongGene ID: 13347 /strong/p
pstrongAppearance: Colorless liquid /strong/p
pstrongConcentration: 0.2 mg/ml /strong/p
pstrongFormulation: 100 micro;g (0.2 mg/ml) immunoaffinity purified rabbit DFF45 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal. /strong/p
pstrongPurification: Affinity purified /strong/p
pstrongSpecies Reactivity: ms/rt /strong/p
pstrongApplication: WB /strong/p
pstrongApplication amp; Usage: Western blotting (0.5-4 micro;g/ml). However, the optimal conditions should be determined individually. The antibody detects the 45 kDa and 28 kDa proteins, corresponding to the apparent molecular weight of DFF45/ICADL, and ICADS in immunoblots. /strong/p
pstrongStorage Temp.: -20 deg;C /strong/p
pstrongShipping : gel pack /strong/p
pstrongShelf Life: 12 months /strong/p
pstrongHandling: The antibody solution should be gently mixed before use. /strong/p
pstrongBrief Background Descriptions: Apoptosis occurs during normal cellular development and involves dramatic changes in cellular structure. Disruption of apoptosis may contribute to cancer as well as many other types of diseases. Recently, a human DNA fragmentation factor (DFF45) was identified. DFF is composed of two subunts: DFF40 and DFF45. Cleavage of DFF45, which is mediated by caspase-3, leads to DFF40rsquo;s activation as a nuclease. Activation of DFF40 can lead to DNA fragmentation, a hallmark of apoptosis. /strong/p