DFF40 Antibody
- 貨號 Cat. No.
- 3049-100
- 規格 Size
- 100 µg
Description
pfont size=2strongAntibody Target :/strongDFF40 /font/p
pstrongHost: Rabbit /strong/p
pstrongAntibody Type: Polyclonal /strong/p
pstrongIsotype: Rabbit IgG /strong/p
pstrongAntibody Form: Affinity Purified Antibody /strong/p
pstrongImmunogen Sequence: Synthetic peptide surrounding amino acid 208 of mouse DFF40 /strong/p
pstrongAccession#: AAH53052 /strong/p
pstrongGene ID: 13368 /strong/p
pstrongAppearance: Colorless liquid /strong/p
pstrongConcentration: 0.2 mg/ml /strong/p
pstrongFormulation: 100 micro;g (0.2 mg/ml) immunoaffinity purified rabbit DFF40 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal. /strong/p
pstrongPurification: Affinity purified /strong/p
pstrongSpecies Reactivity: hu/ms/rt /strong/p
pstrongApplication: WB /strong/p
pstrongApplication amp; Usage: Western blotting (0.5-4 micro;g/ml) and immunohistochemistry (2-8 micro;g/ml). However, the optimal conditions should be determined individually. The antibody detects a 43 kDa DFF40/CAD of human, mouse and rat origins. Mouse kidney tissue lysate can be used as a positive control. /strong/p
pstrongStorage Temp.: -20 deg;C /strong/p
pstrongShipping : gel pack /strong/p
pstrongShelf Life: 12 months /strong/p
pstrongHandling: The antibody solution should be gently mixed before use. /strong/p
pstrongBrief Background Descriptions: DFF is composed of two subunits: DFF40/CAD and DFF45/ICAD. Human DFF45 and its mouse homologue ICAD are the inhibitors of DFF40 and CAD, respectively. Cleavage of DFF45, which is mediated by caspase-3, leads to DFF40rsquo;s activation as a nuclease. Activation of DFF40/CAD can lead to DNA fragmentation, a hallmark of apoptosis. DFF40 mRNA is expressed in limited number of human tissues: pancreas, spleen, prostate, and ovary./strongbr /
nbsp;/p
pstrongHost: Rabbit /strong/p
pstrongAntibody Type: Polyclonal /strong/p
pstrongIsotype: Rabbit IgG /strong/p
pstrongAntibody Form: Affinity Purified Antibody /strong/p
pstrongImmunogen Sequence: Synthetic peptide surrounding amino acid 208 of mouse DFF40 /strong/p
pstrongAccession#: AAH53052 /strong/p
pstrongGene ID: 13368 /strong/p
pstrongAppearance: Colorless liquid /strong/p
pstrongConcentration: 0.2 mg/ml /strong/p
pstrongFormulation: 100 micro;g (0.2 mg/ml) immunoaffinity purified rabbit DFF40 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal. /strong/p
pstrongPurification: Affinity purified /strong/p
pstrongSpecies Reactivity: hu/ms/rt /strong/p
pstrongApplication: WB /strong/p
pstrongApplication amp; Usage: Western blotting (0.5-4 micro;g/ml) and immunohistochemistry (2-8 micro;g/ml). However, the optimal conditions should be determined individually. The antibody detects a 43 kDa DFF40/CAD of human, mouse and rat origins. Mouse kidney tissue lysate can be used as a positive control. /strong/p
pstrongStorage Temp.: -20 deg;C /strong/p
pstrongShipping : gel pack /strong/p
pstrongShelf Life: 12 months /strong/p
pstrongHandling: The antibody solution should be gently mixed before use. /strong/p
pstrongBrief Background Descriptions: DFF is composed of two subunits: DFF40/CAD and DFF45/ICAD. Human DFF45 and its mouse homologue ICAD are the inhibitors of DFF40 and CAD, respectively. Cleavage of DFF45, which is mediated by caspase-3, leads to DFF40rsquo;s activation as a nuclease. Activation of DFF40/CAD can lead to DNA fragmentation, a hallmark of apoptosis. DFF40 mRNA is expressed in limited number of human tissues: pancreas, spleen, prostate, and ovary./strongbr /
nbsp;/p