Antibodies
Dexmedetomidine
- 貨號 Cat. No.
- S3075
- 規格 Size
- 10mM/1mLã€50mg
- 品牌 Brand
- Selleckchem
Description
Dexmedetomidine
Catalog No.S3075
Dexmedetomidine is a sedative medication used by intensive care units and anesthetists.
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Distributor Tel: +886-2-2827-1197jimmy@new.abscience.com.tw
Biological Activity
| Description | Dexmedetomidine is a sedative medication used by intensive care units and anesthetists. | |||||
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| In vitro | Dexmedetomidine has a relatively high ratio of α2/α1-activity (1620:1 as compared with 220:1 for clonidine) and, therefore, is considered a full agonist of the α2 receptor. This may result in more potent effects of sedation without unwanted cardiovascular effects from α1 receptor activation. The 2-h half-life of dexmedetomidine is nearly 4-fold shorter than that of clonidine, which increases the likelihood that a continuous infusion of dexmedetomidine might be useful for sedation. Dexmedetomidine also has minimum alveolar anesthetic concentration (MAC)-sparing properties, but its use as an anesthetic adjuvant has been complicated by persistent hypotension that has mandated IV fluid administration and vasopressor administration. In addition, its use in large doses is complicated by hypertension from α2 receptor-mediated vascular constriction. | |||||
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Protocol(Only for Reference)
References
Chemical Information
| Molecular Weight (MW) | 200.28 |
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| Formula | C13H16N2 |
| CAS No. | 113775-47-6 |
| Storage | 3 years -20℃Powder |
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| 6 months-80℃in DMSO | |
| Syonnyms | N/A |
| Solubility (25°C) * | In vitro | DMSO | 40 mg/mL (199 mM) |
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| Water | 40 mg/mL (199 mM) | ||
| Ethanol | 40 mg/mL (199 mM) | ||
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
| Chemical Name | (S)-5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole |
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Preparing Stock Solutions
| Stock Solution (1ml DMSO) | 1mM | 10mM | 20mM | 30mM |
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| Mass(mg) | 0.20028 | 2.0028 | 4.0056 | 6.0084 |
