DAP5 Polyclonal Antibody
- 貨號 Cat. No.
- 3265-100
- 規格 Size
- 100 ug
Description
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pbHOST:/b Rabbit/p
pbIMMUNOGEN:/b Synthetic peptide surrounding amino acid 808 of human DAP5./p
pbSPECIES REACTIVITY: /bhuman, mouse, rat/p
pbFORMULATION: /b100 ug (0.5 mg/ml) affinity purified rabbit anti-DAP5 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal./p
pbSTORAGE CONDITIONS: /bStore at -20oC. For long term storage, aliquot and freeze at -70oC. Avoid repeated freeze/defrost cycles./p
pbBACKGROUND DESCRIPTION: /bDeath Associated Protein 5 (DAP5) is a 97 kDa protein with high amino acid sequence homology to eukaryotic translation initiation factor 4G (eIF4G). Compared with eIF4G, DAP5 lacks the N-terminal region necessary for cap-dependent translation and has a unique C-terminal part functioning as a regulator for interferon-gamma induced cell death. During apoptosis, DAP5 is cleaved at Asp790. The C-terminal truncated form of DAP5 functions as a cap-independent translation initiation factor responsible for the mediation of its own translation during apoptosis./p
pbAPPLICATION AND USAGE: /bThe antibody can be used for Western blot (0.5-4 ug/ml). However, the optimal conditions should be determined individually. Jurkat, 3T3, and PC12 cell lysates can be used as positive controls./p
pbSPECIFICITY: /bThe antibody detects 97 kDa DAP5 of human, mouse and rat origins. It does not cross react with other DAP family members or with eIF4G. For Research Purpose Only! Not to be used in humans./p
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pbHOST:/b Rabbit/p
pbIMMUNOGEN:/b Synthetic peptide surrounding amino acid 808 of human DAP5./p
pbSPECIES REACTIVITY: /bhuman, mouse, rat/p
pbFORMULATION: /b100 ug (0.5 mg/ml) affinity purified rabbit anti-DAP5 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal./p
pbSTORAGE CONDITIONS: /bStore at -20oC. For long term storage, aliquot and freeze at -70oC. Avoid repeated freeze/defrost cycles./p
pbBACKGROUND DESCRIPTION: /bDeath Associated Protein 5 (DAP5) is a 97 kDa protein with high amino acid sequence homology to eukaryotic translation initiation factor 4G (eIF4G). Compared with eIF4G, DAP5 lacks the N-terminal region necessary for cap-dependent translation and has a unique C-terminal part functioning as a regulator for interferon-gamma induced cell death. During apoptosis, DAP5 is cleaved at Asp790. The C-terminal truncated form of DAP5 functions as a cap-independent translation initiation factor responsible for the mediation of its own translation during apoptosis./p
pbAPPLICATION AND USAGE: /bThe antibody can be used for Western blot (0.5-4 ug/ml). However, the optimal conditions should be determined individually. Jurkat, 3T3, and PC12 cell lysates can be used as positive controls./p
pbSPECIFICITY: /bThe antibody detects 97 kDa DAP5 of human, mouse and rat origins. It does not cross react with other DAP family members or with eIF4G. For Research Purpose Only! Not to be used in humans./p