Antibodies
Dacarbazine
- 貨號 Cat. No.
- S1221
- 規格 Size
- 10mM/1mLã€50mg
- 品牌 Brand
- Selleckchem
Description
Dacarbazine
Catalog No.S1221
Dacarbazine is an antineoplastic chemotherapy drug used in the treatment of various cancers.
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Distributor Tel: +886-2-2827-1197jimmy@new.abscience.com.tw
Biological Activity
Dacarbazine(DTIC-Dome) is an antineoplastic chemotherapy drug used in the treatment of various cancers, among them malignant melanoma, Hodgkin lymphoma, sarcoma, and islet cell carcinoma of the pancreas. [1]
Dacarbazine belongs to the family of chemicals known as alkylating agents. Dacarbazine alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis. [2]
Dacarbazine is normally administered by injection (a shot) or intravenous infusion (IV) under the immediate supervision of a doctor or nurse. [1]
Chemical Information
| Molecular Weight (MW) | 182.18 |
|---|---|
| Formula | C6H10N6O |
| CAS No. | 4342-03-4 |
| Storage | 3 years -20℃Powder |
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| 6 months-80℃in DMSO | |
| Syonnyms | DTIC |
| Solubility (25°C) * | In vitro | DMSO | 3 mg/mL (16 mM) |
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| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | <1 mg/mL (<1 mM) | ||
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
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Preparing Stock Solutions
| Stock Solution (1ml DMSO) | 1mM | 10mM | 20mM | 30mM |
|---|---|---|---|---|
| Mass(mg) | 0.18218 | 1.8218 | - | - |
