Cytokeratin-5 (3E2F) Antibody

Cytokeratins are proteins of keratin-containing intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue. Cytokeratins form a complex network extending from the nucleus to the cell membrane. This network is involved in cellular communication and cytoplasmic organization. Defects in cytokeratin-5 are implicated in numerous skin diseases, including epidermolysis bullosa simplex Dowling-Meara type and Dowling-Degos disease.