Proteins and Peptides
CXCR4 Antibody (LS-B2773)
- 貨號 Cat. No.
- LS-B2773
- 規格 Size
- 50 µg
- 品牌 Brand
- LSBio
Description
| Antibody Catalog ID: | LS-B2773 |
|---|---|
| Antibody Validation: | This antibody replaces catalog number LS-C6296. It has been validated for use in the following assays: IHC-P. |
| Antibody Target: | CXCR4 |
| Synonyms: | CXCR4 Antibody, c-x-c chemokine receptor 4 Antibody, CD184 Antibody, chemokine c-x-c motif receptor 4 Antibody, cmkar4 Antibody, cxc chemokine receptor 4 Antibody, CXC-R4 Antibody, CXCR-4 Antibody, cxcr4 Antibody, d2s201e Antibody, FB22 Antibody, fusin Antibody, hm89 Antibody, hsy3rr Antibody, LAP3 Antibody, LCR1 Antibody, lestr Antibody, npy3r Antibody, NPYR Antibody, NPYRL Antibody, npyy3 Antibody, npyy3r Antibody, WHIM Antibody |
| Family: | GPCR |
| Subfamily: | Chemokine |
| Host: | CXCR4 antibody was produced in Goat |
| Antigen Species: | CXCR4 antibody was raised against Human |
| Clonality: | Polyclonal |
| Antigen Type: | Synthetic peptide |
| Immunogen: | CXCR4 antibody was raised against synthetic peptide corresponding to aa 13-38 (CT[13]EEMGSGDYDSMKEPCFREENANFNK[38]) of the N-terminal extracellular domain of human CXCR4 (CXC chemokine receptor 4). |
| Antibody Specificity: | Recognizes human CXCR4. |
| Antigen Modification: | aa13-38 |
| Purification: | Immunoaffinity Chromatography |
| Presentation: | PBS, pH 7.2, 1 mg/ml BSA, 0.1% sodium azide. |
| Recommended Storage: | +4°C or -20°C, Avoid repeated freezing and thawing. |
| Antibody Usage Summary: | Immunohistochemistry: LS-B2773 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody LS-D3, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2773 was determined to be 5 ug/ml. Immunocytochemistry (Acetone fixed cells): 1:300. Function: Blocks SDF mediated stimulation of DU-145 cells. Positive control: Human peripheral blood cells. |
| Antibody Uses: | Immunohistochemistry - Paraffin (IHC-P) (5 µg/ml), Immunocytochemistry (ICC) (1:300), Western blot (WB) (1:1000), Functional Assay (Func) (Optimal dilution to be determined by the researcher) |
| Size: | 50 µg |
| Concentration: | 2 mg/ml |
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