CX-5461
Chemical Compounds
- 貨號 Cat. No.
- M2293
- 規格 Size
- 10mg,50mg
- 品牌 Brand
- No Brand
Description
CX-5461 is a potent small-molecule rRNA synthesis inhibitor with an IC50 of 0.11 μM. CX-5461 selectively blocks RNA PolI transcription,PIC assembly and SL1-rDNA interaction. CX-5461 indicates potent antiproliferative activity in cancer cells and induces autophagy incancer cells. CX-5461 shows potent antitumor activity in A375 and MiaPaca xenografts.
