cTnI (3A10) Antibody

Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. Troponin I binds to actin and tropomyosin. Defects in Troponin I are the cause of cardiomyopathies characterized by ventricular anomalies.