CREB (Ser133) Antibody
Antibodies
- 貨號 Cat. No.
- 252530
- 規格 Size
- 0.1 ml
- 品牌 Brand
- Abbiotec
- Application 應用
- ELISA
- Reactivity
- B 、 Canine 、 Chicken 、 Human 、 Mouse 、 Rat 、 Sheep 、 X
Description
As a dimer, CREB-1 (cAMP-responsive element-binding protein 1) binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters, to stimulate transcription. CREB-1 is activated by phosphorylayion on Ser-133 and Ser-142. Transcriptional activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. CREB-1 has been implicated in synchronization of circadian rhythmicity. It interacts with various proteins including TORC/CRTC, CREBBP, ARRB1.
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