Proteins and Peptides
CR1 Antibody (LS-B2556)
- 貨號 Cat. No.
- LS-B2556
- 規格 Size
- 50 µg
- 品牌 Brand
- LSBio
Description
| Antibody Catalog ID: | LS-B2556 |
|---|---|
| Antibody Validation: | This antibody replaces catalog number LS-C45218. It has been validated for use in the following assays: IHC-P. |
| Antibody Target: | CR1 |
| Synonyms: | CR1 Antibody, C3-binding protein Antibody, C3BR Antibody, C4BR Antibody, CD35 Antibody, complement component C3b/C4b receptor Antibody, complement receptor type 1 Antibody, KN Antibody |
| Family: | Protease |
| Subfamily: | Serine S1 |
| Host: | CR1 antibody was produced in Mouse |
| Antigen Species: | CR1 antibody was raised against Human |
| Clonality: | Monoclonal |
| Isotype: | IgG1 |
| Antibody Clone Name: | E11 |
| Antigen Type: | Cells |
| Immunogen: | CR1 antibody was raised against human acute monocytic leukaemia cells |
| Antibody Specificity: | Is a single chain cell surface glycoprotein which exists in four allotypic forms (A, B, C, D) of 190kD, 220kD, 160kD and 250kD respectively. The molecule is expressed by granulocytes, monocytes, B cells and some T cells. Functionally CD35 acts as a receptor for the C3b component of complement. Clone E11 has been reported to be suitable for use in Western Blot. |
| Predicted Species Reactivity: | Baboon, Monkey |
| Purification: | Protein A Column |
| Presentation: | PBS, pH 7.4. |
| Recommended Storage: | +4°C or -20°C, Avoid repeated freezing and thawing. |
| Antibody Usage Summary: | Immunohistochemistry: LS-B2556 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody LS-D2, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2556 was determined to be 10 ug/ml. Flow Cytometry: Use 10 ul of the diluted antibody to label 10^6 cells or 100 ul whole blood. Histology Positive Control Tissue: Tonsil. |
| Antibody Uses: | Immunohistochemistry - Paraffin (IHC-P) (10 µg/ml), Immunohistochemistry - Frozen (IHC-Fr), Flow Cytometry (Flo) (1:50 - 1:100) (Optimal dilution to be determined by the researcher) |
| Size: | 50 µg |
| Concentration: | 1 mg/ml |
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