Corynebacterium Diphtheriae Toxoid (17.6B9) Antibody

h1 class=titleCorynebacterium Diphtheriae Toxoid (17.6B9) Antibody/h1
div id=node-547 class=node ntype-antibodiesMouse Monoclonal
div class=contentstyle type=text/css
!--
h4 {
margin: 30px 0 0 0;
padding: 0;
border-top: 1px solid #bbb;
background: #f8f8f8;
}
--/style
div class=product-table
table border=0 cellspacing=10 cellpadding=0 width=100%
tbody
tr
td valign=top width=50%
h4Catalog Number/h4
pstrong250347/strong/p
h4Unit/h4
pstrong0.2 mg /strong/p
h4Format/h4
pEach vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography./p
pnbsp;/p
h4Data and Images/h4
/td
td valign=top
h4Description/h4
pCorynebacterium diphtheriae is a Gram-positive, non-motile bacterium that can cause serious illness in unvaccinated humans. C. diphtheriae infects the epithelial cells of the upper respiratory tract from where they secrete a potent toxin that is absorbed and disseminated through lymph channels and blood to the susceptible tissues of the body. The toxin is a single protein chain of 62 kDa which is quot;nickedquot; at proteolytic processing sites to produce an A chain of 21 kDa and a B chain of 40 kDa, held together by a disulfide bridge. The A-chain carries the ADP-ribosylation enzymatic activity responsible for the toxic action. This antibody reacts with diphtheria toxoid and also neutralizes diphtheria toxin in a VERO cell assay./p
br style=clear: both /
br style=clear: both /
h4Product Citations/h4
pnbsp;/p
h4Recommended Products/h4
pa href=http://abbiotec.com/antibodies/corynebacterium-diphtheriae-toxoid-%2811d9%29-antibody250348 Corynebacterium Diphtheriae Toxoid (11D9) Antibody/abr /
nbsp;/p
h4Alternate Names/h4
pDT;nbsp; NAD(+)--dipthamide ADP-ribosyltransferase/p
h4Accession No./h4
pa class=accession-link target=_blank href=http://www.expasy.org/uniprot/P00588P00588/abr /
nbsp;/p
h4Clonality/h4
p17.6B9/p
h4Antigen/h4
pnbsp;/p
pDiphtheria toxoid prepared from toxin purified from C. diphtheriae subsp. intermedius Park-Williams no. 8 by formaldehyde inactivation (2), and adsorbed to aluminum hydrtoxide gel./p
pnbsp;/p
h4Application Notes/h4
pnbsp;/p
pProduct Cat. No. 250347 reacts strongly with diphtheria toxoid in sandwich ELISA in combination with a polyclonal antibody against the toxoid as capture antibody. The antibody also reacts in ELISA with diphtheria toxoid coated directly onto the microtiter well. Biotinylated Product Cat. No. 250347 can be used as a detection antibody in a sandwich ELISA with Product Cat. No. 250348 used as a capture antibody.nbsp;nbsp;/p
pE: 1:35,000/p
pstrongReacts with/strongnbsp; :Other/p
pnbsp;/p
h4Storage/h4
pStore at 4deg;C. Product is guaranteed 6 months from the date of shipment./p
/td
/tr
/tbody
/table
/div
/div
/div