Corynebacterium Diphtheriae Toxoid (11D9) Antibody

h1 class=titleCorynebacterium Diphtheriae Toxoid (11D9) Antibody/h1
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h4Catalog Number/h4
pstrong250348/strong/p
h4Unit/h4
pstrong0.2 mg /strong/p
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Format/h4
pEach vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography./p
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h4Description/h4
pCorynebacterium diphtheriae is a Gram-positive, non-motile bacterium that can cause serious illness in unvaccinated humans. C. diphtheriae infects the epithelial cells of the upper respiratory tract from where they secrete a potent toxin that is absorbed and disseminated through lymph channels and blood to the susceptible tissues of the body. The toxin is a single protein chain of 62 kDa which is quot;nickedquot; at proteolytic processing sites to produce an A chain of 21 kDa and a B chain of 40 kDa, held together by a disulfide bridge. The A-chain carries the ADP-ribosylation enzymatic activity responsible for the toxic action. This antibody reacts with diphtheria toxoid./p
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h4Product Citations/h4
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h4Recommended Products/h4
pa href=http://abbiotec.com/antibodies/corynebacterium-diphtheriae-toxoid-%2817.6b9%29-antibody250347 Corynebacterium Diphtheriae Toxoid (17.6B9) Antibody/abr /
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h4Alternate Names/h4
pDT;nbsp; NAD(+)--dipthamide ADP-ribosyltransferase/p
h4Accession No./h4
pa class=accession-link target=_blank href=http://www.expasy.org/uniprot/P00588P00588/abr /
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h4Clonality/h4
p11D9/p
h4Antigen/h4
pnbsp;/p
pDiphtheria toxoid prepared from toxin purified from C. diphtheriae subsp. intermedius Park-Williams no. 8 by formaldehyde inactivation (2), and adsorbed to aluminum hydrtoxide gel/p
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h4Application Notes/h4
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pProduct Cat. No. 250348 reacts in ELISA wells coated with diphtheria toxoid. Product Cat. No. 250348 detects in western blot a band at approximately 63 kDa corresponding to the toxin proenzyme. Biotinylated Product Cat. No. 250347 can be used as a detection antibody in a sandwich ELISA with Product Cat. No. 250348 used as a capture antibody./p
pE: 1:8,000/p
pWB: 1:500/p
pstrongReacts with/strongnbsp; :Other/p
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h4Storage/h4
pStore at 4deg;C. Product is guaranteed 6 months from the date of shipment./p
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