Collagen IV (Mouse) Antibody

h1 class=titleCollagen IV (Mouse) Antibody/h1
div id=node-1384 class=node ntype-antibodiesRabbit Polyclonal
div class=contentstyle type=text/css
!--
h4 {
margin: 30px 0 0 0;
padding: 0;
border-top: 1px solid #bbb;
background: #f8f8f8;
}
--/style
div class=product-table
table border=0 cellspacing=10 cellpadding=0 width=100%
tbody
tr
td valign=top width=50%
h4Catalog Number/h4
pstrong250485/strong/p
h4Unit/h4
pstrong0.1 mg/strong/p
h4
pnbsp;/p
Format/h4
pEach vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography./p
pnbsp;/p
h4Data and Images/h4
div class=field field-type-text field-field-data-img-01
div class=field-items
div class=field-item
pspan class=inline lefta href=http://www.abbiotec.com/image/collagen-iv-staining-rat-kidneyimg class=image image-medium title=Collagen IV staining in rat kidney: Paraffin-embedded rat kidney is stained with Collagen IV (Mouse) Antibody (Cat. No. 250485) used at 1:200 dilution. alt=Collagen IV staining in rat kidney: Paraffin-embedded rat kidney is stained with Collagen IV (Mouse) Antibody (Cat. No. 250485) used at 1:200 dilution. width=300 height=240 src=http://www.abbiotec.com/files/images/250485_ratkidney.medium.jpg //aspan style=width: 298px class=captionstrongCollagen IV staining in rat kidney: /strongParaffin-embedded rat kidney is stained with Collagen IV (Mouse) Antibody (Cat. No. 250485) used at 1:200 dilution./span/span/p
/div
/div
/div
/td
td valign=top
h4Description/h4
pType IV collagen is the major structural component of glomerular basement membranes forming a quot;chicken-wirequot; meshwork together with laminins, proteoglycans and entactin/nidogen. There are six type IV collagen isoforms, alpha 1(IV)-alpha 6(IV), each of which can form a triple helix strucuture with 2 other chains to generate type IV collagen network. Defects in type IV collagen are a cause of Alport syndrome autosomal recessive (APSAR), characterized by glomerulonephritis, renal failure, sensorineural deafness and eye abnormalities. Defects in type IV collagen are also a cause of benign familial hematuria (BFH). The antibody is directed against rodent alpha 1 isoform./p
br style=clear: both /
br style=clear: both /
h4Product Citations/h4
pnbsp;/p
h4Recommended Products/h4
pbr /
nbsp;/p
h4Alternate Names/h4
pCollagen alpha-4(IV) chain; COL4A4/p
h4Accession No./h4
pa class=accession-link target=_blank href=http://www.expasy.ch/uniprot/Q9QZR9Q9QZR9/abr /
nbsp;/p
h4Clonality/h4
pnbsp;/p
h4Antigen/h4
pnbsp;/p
pKLH-conjugated synthetic peptide encompassing a sequence within the center region of mouse type IV collagen (isoform alpha 1)./p
pnbsp;/p
h4Application Notes/h4
pnbsp;/p
pProduct Cat. No. 250485 is directed against alpha 1 isoform./p
pE: 1:500-1:1,000/p
pWB: 1:200-1:500/p
pIHC: 1:200-1:500/p
pstrongReacts with/strongnbsp; : M | R/p
pnbsp;/p
h4Storage/h4
pStore at -20deg;C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment./p
/td
/tr
/tbody
/table
/div
/div
/div