COL4A1 (G46) Antibody

貨號 Cat. No.
BS1072
規格 Size
100μg
品牌 Brand
Bioworld

Description

stock



Host: Rabbit


Reactivity: Human,Mouse



Product


1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.




Purification & Purity


The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).




Specificity


Collagen IV (G46) antibody detects endogenous levels of Collagen IV protein.




Applications (Recommended Dilutions)


WB: 1:500~1:1000 IHC: 1:50~1:200






Western Blot(WB)



Western blot (WB) analysis of Collagen IV (G46) antibody in extracts from HeLa cell.





Immunohistochemistry (IHC)



Immunohistochemistry (IHC) analyzes of Collagen IV (G46) antibody in paraffin-embedded human breast carcinoma tissue.





Storage&Stability


Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.




Background


The extensive family of COL gene products (collagens) is composed of several chain types, including fibril-forming interstitial Collagens (Types I, II, III and V) and basement membrane Collagens (Type IV), each type containing multiple isoforms. Collagens are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue, such as tendons and cartilage. All collagens contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. Several collagens also play a role in cell adhesion, important for maintaining normal tissue architecture and function.


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