COBRA1 Antibody
Antibodies
- 貨號 Cat. No.
- 253121
- 規格 Size
- 0.1 ml
- 品牌 Brand
- Abbiotec
- Application 應用
- ELISA
- Reactivity
- Human 、 Mouse 、 Rat 、 Rb
Description
Cofactor of BRCA1 (negative elongation factor B, NELF-B, COBRA1) is an essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. COBRA1 can induce chromatin unfolding.
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