CNX-1351
Chemical Compounds
- 貨號 Cat. No.
- M3730
- 規格 Size
- 5mg,10mg,50mg
- 品牌 Brand
- No Brand
Description
CNX-1351 potently inhibited PI3Kα and was 20−400 times less potent against β, γ, and δ. CNX-1351 inhibits PI3Kα signaling in cells and shows prolonged inhibition consistent with a covalent mechanism of Action. CNX-1351 inhibits growth of cells dependent on PI3Kα. CNX-1351 also inhibits PI3Kα signaling in vivo and bonds to p110α.
