Clofarabine
Chemical Compounds
- 貨號 Cat. No.
- M1698
- 規格 Size
- 10mg,50mg, 200mg
- 品牌 Brand
- No Brand
Description
Clofarabine inhibits the enzymatic activities of ribonucleotide reductase (IC50 = 65 nM) and DNA polymerase. Induces apoptosis by directly altering mitochondrial transmembrane potential. Demonstrates growth inhibition and cytotoxic activity in a variety of leukemias and solid tumors.
