CHRNA4 Antibody
Antibodies
- 貨號 Cat. No.
- 251410
- 規格 Size
- 0.1 mg
- 品牌 Brand
- Abbexa
- Application 應用
- ELISA 、 IHC 、 WB
- Reactivity
- Human 、 Mouse 、 Rat
Description
After binding acetylcholine, the neuronal acetylcholine receptor (CHRNA4) responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Defects in CHRNA4 are the cause of nocturnal frontal lobe epilepsy type 1 (ENFL1), also symbolized ADNFLE. ENFL1 is an autosomal dominant epilepsy characterized by nocturnal seizures with hyperkinetic automatisms and poorly organized stereotyped movements.
