Antibodies
Chlorpromazine HCl
- 貨號 Cat. No.
- S2456
- 規格 Size
- 10mM/1mLã€50mg
- 品牌 Brand
- Selleckchem
Description
Chlorpromazine HCl
Catalog No.S2456
Chlorpromazine HCl is a dopamine and potassium channel inhibitor with IC50 of 6.1 and 16 μM for nward-rectifying K+ currents and time-independent outward currents
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Distributor Tel: +886-2-2827-1197jimmy@new.abscience.com.tw
Biological Activity
Chlorpromazine (Sonazine) is a dopamine and potassium channel inhibitor with IC50 of 6.1 and 16 µM for nward-rectifying K+ currents and time-independent outward currents.In inhibits prolactin release inhibitory factor, thus stimulating the release of prolactin. The turnover of dopamine in the brain is also increased. [1] Chlorpromazine blocks a variety of K+ channels in heart muscle cells. Inasmuch as the potency of inhibition is less than the previously reported use-dependent block of Na+ channels, the cardiovascular adverse effects of chlorpromazine are probably caused mainly by the latter effect. [2]
Chemical Information
Download Chlorpromazine HCl SDF
| Molecular Weight (MW) | 355.33 |
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| Formula | C17H19ClN2S.HCl |
| CAS No. | 69-09-0 |
| Storage | 3 years -20℃Powder |
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| 6 months-80℃in DMSO | |
| Syonnyms | Promacid |
| Solubility (25°C) * | In vitro | DMSO | 71 mg/mL (199 mM) |
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| Water | 71 mg/mL (199 mM) | ||
| Ethanol | 71 mg/mL (199 mM) | ||
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
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Preparing Stock Solutions
| Stock Solution (1ml DMSO) | 1mM | 10mM | 20mM | 30mM |
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| Mass(mg) | 0.35533 | 3.5533 | 7.1066 | 10.6599 |
