CGRP Antibody

The calcitonin family of bioactive peptides comprises of calcitonin, amylin, adrenomedullin (ADM) and two calcitonin-gene related peptides (CGRP1 and CGRP2). CGRP is a 37-aa peptide produced by tissue specific processing of calcitonin. Calcitonin is the major product in the thyroid, whereas CGRP is prominent in neural tissues. CGRP is a potent cardiovascular agent with structural similarity with amylin. CGRP is found in two isoforms (CGRP-I and CGRP-II) that differ only by 3 amino acids.