CGK 733

貨號 Cat. No.
A13191-10
規格 Size
10mg
品牌 Brand
AdooQ

Description




Technical details








































CATALOG NUM



A13191



M. WT



555.84



FORMULA



C23H18Cl3FN4O3S



PURITY



>98%



STORAGE



at -20°C 3 years Powder



CAS NO.



905973-89-9



SYNONYMS



CGK733,CGK-733



SMILES



C1=CC=C(C=C1)C(C2=CC=CC=C2)C(=O)NC(C(Cl)(Cl)Cl)NC(=S)NC3=CC(=C(C=C3)F)[N+](=O)[O-]




Biological Activity


CGK733 is a selective inhibitor of ATR and ATM kinases. Induces cell death in prematurely senescent breast cancer cells.


Solubility *




























In vitro



DMSO



100 mg/mL (179.9 mM)





Water



<1 mg/mL (<1 mM)





Ethanol



<1 mg/mL (<1 mM)



* <1 mg/ml means slightly soluble or insoluble.


* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.








Preparing Stock Solutions






































Concentration / Solvent Volume / Mass



1 mg



5 mg



10 mg



0.1 mM



17.99 mL



89.95 mL



179.91 mL



0.5 mM



3.6 mL



17.99 mL



35.98 mL



1 mM



1.8 mL



9 mL



17.99 mL



5 mM



0.36 mL



1.8 mL



3.6 mL




*The above data is based on the productmolecular weight 555.84. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.


 



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