CFTR Peptide

h1 class=titleCFTR Peptide/h1
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h4Catalog Number/h4
pstrong350548/strong/p
h4Unit/h4
pstrong0.1 mg/strong/p
h4Price/h4
pstrong$50.00/strong/p
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h4Description/h4
pCystic fibrosis transmembrane conductance regulator (CFTR), a ABC transporter, is involved in the transport of chloride ions and regulates bicarbonate secretion in epithelial cells by regulating the SLC4A7 transporter. CFTR is localized in aggresome bodies when proteasome's degradative capacity is exceeded and lysosomal degradation is engaged via autophagy. Defects in CFTR are the cause of cystic fibrosis./p
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h4Format/h4
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pEach vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect./p
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h4Data and Images/h4
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h4Product Citations/h4
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h4Recommended Products/h4
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a href=http://abbiotec.com/antibodies/cftr-antibody200186 CFTR Antibody/abr /
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h4Alternate Names/h4
pCystic fibrosis transmembrane conductance regulator; CFTR; cAMP-dependent chloride channel; ATP-binding cassette transporter sub-family C member 7; ABCC7/p
h4Accession No./h4
pa class=accession-link href=http://www.expasy.org/uniprot/P13569 target=_blankP13569/abr /
a class=accession-link href=http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=proteinamp;id=90421313 target=_blankNP_000483/abr /
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h4MW/h4
p2238.5 g/mol/p
h4Sequence/h4
pThe synthetic peptide used to raise the antibody Cat. No. 200186 is selected from a sequence within the N-term region of human CFTR. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended./p
h4Composition/h4
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pC98H160N30O28S1/p
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h4Purity/h4
pPurity gt; 80% by HPLC/p
h4Solubility/h4
pDistilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile./p
h4Storage/h4
pStore at -20deg;C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20deg;C./p
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