CFTR Antibody

h1 class=titleCFTR Antibody/h1
div id=node-2718 class=node ntype-antibodiesRabbit Polyclonal
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h4Catalog Number/h4
pstrong251639/strong/p
h4Unit/h4
pstrong0.1mg/strong/p
h4Isotype/h4
Rabbit Ig
h4Applications/h4
E, WB, IHC
h4Species reactivity/h4
H, M, R, Other
h4Format/h4
pnbsp;/p
pEach vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography./p
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h4Description/h4
pCystic fibrosis transmembrane conductance regulator (CFTR), a ABC transporter, is involved in the transport of chloride ions and regulates bicarbonate secretion in epithelial cells by regulating the SLC4A7 transporter. CFTR is localized in aggresome bodies when proteasome's degradative capacity is exceeded and lysosomal degradation is engaged via autophagy. Defects in CFTR are the cause of cystic fibrosis./p
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h4Alternate Names/h4
pCFTR; Cystic fibrosis transmembrane conductance regulator; Channel conductance-controlling ATPase; cAMP-dependent chloride channel; ATP-binding cassette transporter sub-family C member 7; ABCC7/p
h4Accession No./h4
pa class=accession-link href=http://www.uniprot.org/uniprot/P13569 target=_blankP13569/abr /
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h4Antigen/h4
pnbsp;/p
pKLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CFTR./p
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h4Application Notes/h4
pnbsp;/p
pE: 1:500-1:1,000br /
WB: 1:100-1:500br /
IHC: 1:100-1:500/p
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h4Storage/h4
pnbsp;/p
pStore at -20deg;C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment./p
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