CETP Inhibitor Screening Kit (Fluorometric) II
Kits
- 貨號 Cat. No.
- K594-100
- 規格 Size
- K594-100
- Reactivity
- Mammalian
- Sample Type
- as well as many other biological fluids 、 Cell and tissue culture supernatants 、 Plasma 、 Serum 、 urine
Description
Alternate Name :
Tag Line :
The most advanced kit on the market - includes human CETP enzyme and CETP inhibitor Anacetrapib
Storage Conditions: 4°C
Shelf life: 12 months
Summary :
• Detection method - Fluorescence (Ex/Em 480/511 nm)
• Species reactivity- Mammalian
Detection Method: Fluorescence (Ex/Em 480/511 nm)
Features & Benefits:
• The most advanced kit on the market - includes human CETP enzyme and CETP inhibitor Anacetrapib for ultimate user-convenience. • Simple and sensitive assay • High-Throughput adaptable
Description:
Cholesteryl ester transfer protein (CETP) is a plasma protein that transfers a cholesteryl ester from HDL to LDL or VLDL in exchange for a triglyceride. HDL plays an important role in lipid metabolism and cardiovascular health. HDL transports cholesterol to the liver for excretion or to steroidogenic tissues for steroid synthesis. HDL also plays an important role in the reverse cholesterol transport pathway, removing cholesterol from lipid-filled macrophages, protecting against atherosclerosis. Because of this function, CETP is viewed as a target to increase HDL, with CETP inhibition being an active area of research and several CETP inhibitors at various stages of drug development. BioVision’s CETP Inhibitor Screening Kit uses a self-quenched fluorescent neutral lipid that can be measured when transferred to an acceptor molecule. The fluorometric intensity is directly proportional to the amount of neutral lipid transfer. Enriched Human CETP from plasma is included for screening. A CETP inhibitor (Anacetrapib) is included as a positive control.