Cerulenin

50 mg. >98% purity. Chemical name: 2,3-Epoxy-4-oxo-7,10-dodecadienamide. Fatty acid synthase (FAS) inhibitor reported to bind in equimolar ratio to ?-keto-acyl-ACP synthase, thus inhibiting protein acylation. Produces metabolic effects similar to effects of leptin, but through mechanisms that are independent of, or down-stream from, both leptin and melanocortin receptors. Apoptosis inducer. Inhibitor of bacterial fatty acid synthesis (inhibits FabH, FabB and FabF condensation enzymes). Soluble in DMSO. store at +4C and protect from light.