CDKN2A Peptide
Proteins and Peptides
- 貨號 Cat. No.
- 350509
- 規格 Size
- 0.1 mg
- 品牌 Brand
- Abbiotec
Description
CDKN2A acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This interaction inhibits CDKs binding to cyclins D and phosphorylation of the retinoblastoma protein. Defects in CDKN2A are the cause of numerous cancers such as melanoma and astrocytoma.