CDKN2A Antibody

Antibodies

貨號 Cat. No.: 200147
規格 Size: 0.1 mg
品牌 Brand: Abbiotec
Application 應用: ELISA
Reactivity: Human

Description

CDKN2A acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This interaction inhibits CDKs binding to cyclins D and phosphorylation of the retinoblastoma protein. Defects in CDKN2A are the cause of numerous cancers such as melanoma and astrocytoma.

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