Cdk2 (V154) Antibody

貨號 Cat. No.
BS1049
規格 Size
100μg
品牌 Brand
Bioworld

Description

stock



Host: Rabbit


Reactivity: Human,Mouse,Rat


 













































Host   Reactivity Size Application stock price cart
BS1049 H,M,R 100μg WB 218.00
Contact information


 


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                     -----Price For USA Only------



Bioworld Technology,Inc.

 8201 Central Ave NE • Suite O Minneapolis, MN 55432  USA

 Tel: 612-326-3284

 Email: info@bioworlde.com







Product


1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.




Purification & Purity


The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).




Specificity


CDK2 (V154) antibody detects endogenous levels of CDK2 protein.




Applications (Recommended Dilutions)


WB: 1:500~1:1000






Western Blot(WB)



Western blot (WB) analysis of CDK2 (V154) antibody in extracts from A2780 cells.





Storage&Stability


Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.




Background


In vertebrates, as in yeast, multiple cyclins have been identified, including a total of eight such regulatory proteins in mammals. In contrast to the situation in yeast, the Cdc2 p34 kinase is not the only catalytic subunit identified in vertebrates that can interact with cyclins. While Cdc2 p34 is essential for the G2 to M transition in vertebrate cells, a second Cdc2-related kinase has also been implicated in cell cycle control. This protein, designated cyclindependent kinase 2 (Cdk2) p33, also binds to cyclins and its kinase activity is temporally regulated during the cell cycle. Several additional Cdc2 p34- related cyclin dependent kinases have been identified. These include Cdk3, Cdk4, Cdk5, PCTAIRE-1, PCTAIRE-2, PCTAIRE-3, Cdk6 Cdk7, Cdk8 and KKIALRE.



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