CD8 (HIT8a) Antibody

h1 class=titleCD8 (HIT8a) Antibody/h1
div id=node-1808 class=node ntype-antibodiesMouse Monoclonal, FITC-conjugated
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h4Catalog Number/h4
pstrong250997/strong/p
h4Unit/h4
pstrong2 ml/strong/p
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pnbsp;/p
Format/h4
pEach vial contains 2 ml IgG (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography./p
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h4Description/h4
pCD8 antibody recognizes CD8 antigen which is 68 KD typeâ… transmembrane glycoprotein, and consists of two disulfide-linked chains that form either as alpha;/alpha; homodimers or alpha;/beta;heterodimers. The most CD8 antigen is CD8alpha;/beta;heterodimer expressed mainly on 13-48% (about one-third of peripheral T cells) of peripheral blood lymphocytesndash;suppressor/cytotoxic T lymphocytes (Ts/Tc) and 70-80% of thymocytes. In addition, a proportion of gamma;delta;T cells and NK cells express CD8alpha; homodimers. CD8a can form homodimers, but CD8beta;cannot. CD8beta;requires the presence of CD8a to be expressed on the cell surface. CD8 antigen is co receptor for HLA classâ… molecule./p
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h4Product Citations/h4
pnbsp;/p
pSchlossman S., L. Bloumsell, W. Gilks, et al., eds. 1995. Leucocyte Typing Ⅴ: White Cell Differentiation Antigens. P：1196，1217，1230，2003nbsp; Oxford University Press, New York./p
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h4Recommended Products/h4
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h4Alternate Names/h4
pT-cell surface glycoprotein CD8 alpha chain; T-lymphocyte differentiation antigen T8/Leu-2; CD8a antigen; CD8a; MAL/p
h4Accession No./h4
pa class=accession-link target=_blank href=http://www.expasy.ch/uniprot/P01732P01732/abr /
a class=accession-link target=_blank href=http://www.ncbi.nlm.nih.gov/protein/91105174NP_001761/abr /
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h4Clonality/h4
pHIT8a/p
h4Antigen/h4
pnbsp;/p
h4Application Notes/h4
pnbsp;/p
pFACS with whole blood: 100 mu;l blood + 20 mu;l antibody; FACS with cells: 10E6 cells + 20 mu;l antibody. E: 1:500-1:1,000/p
pFACS: 1:200-1:1,000/p
pIHC: 1:200-1:500/p
pIF:Use at an assay dependent concentration/p
pstrongReacts with/strongnbsp; :H/p
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h4Storage/h4
pStore at 4deg;C. Product is guaranteed 6 months from the date of shipment./p
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