CD8 (HIT8a) Antibody

h1 class=titleCD8 (HIT8a) Antibody/h1
div id=node-1213 class=node ntype-antibodiesMouse Monoclonal
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h4Catalog Number/h4
pstrong250941/strong/p
h4Unit/h4
pstrong0.1 mg/strong/p
h4Format/h4
pEach vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography./p
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h4Description/h4
pThe CD8 (HIT8a) antibody recognizes a 68-kDa type-I transmembrane glycoprotein that consists of two disulfide-linked chains that form alpha homodimers or alpha/beta heterodimers. The most frequent CD8 antigen is CD8 alpha/beta heterodimer, which is expressed on 13-48 % peripheral blood suppressor/cytotoxic T lymphocytes (Ts/Tc) and 70-80% thymocytes. In addition, a proportion of gamma;delta;T cells and NK cells express CD8alpha; homodimers. CD8beta; requires the presence of CD8a to be expressed on the cell surface. CD8 antigen is co-receptor for HLA class-I molecules./p
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h4Product Citations/h4
pnbsp;/p
pSchlossman SL, Bloumsell W, Gilks et al., eds. 1995. Leucocyte Typing V: White Cell Differentiation Antigens. P: 1196, 1217, 1230, 2003 Oxford University Press, New York./p
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h4Recommended Products/h4
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h4Alternate Names/h4
pT-cell surface glycoprotein CD8 alpha chain; T-lymphocyte differentiation antigen T8/Leu-2; CD8a antigen; CD8a; MAL/p
h4Accession No./h4
pa class=accession-link target=_blank href=http://www.expasy.ch/uniprot/P01732P01732/abr /
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h4Clonality/h4
pHIT8a/p
h4Antigen/h4
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h4Application Notes/h4
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pPurified antibody is suitable for immunohistochemistry with acetone-fixed frozen and formalin-fixed paraffin sections./p
pE: 1:500-1:1,000/p
pFACS: 1:200-1:1,000/p
pIHC: 1:200-1:500/p
pstrongReacts with/strongnbsp; :H/p
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h4Storage/h4
pStore at -20deg;C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment./p
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