CD71 (HI166) Antibody

h1 class=titleCD71 (HI166) Antibody/h1
div id=node-1105 class=node ntype-antibodiesMouse Monoclonal
div class=contentstyle type=text/css
!--
h4 {
margin: 30px 0 0 0;
padding: 0;
border-top: 1px solid #bbb;
background: #f8f8f8;
}
--/style
div class=product-table
table border=0 cellspacing=10 cellpadding=0 width=100%
tbody
tr
td valign=top width=50%
h4Catalog Number/h4
pstrong250979/strong/p
h4Unit/h4
pstrong0.1 mg/strong/p
h4
pnbsp;/p
Format/h4
pEach vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography./p
pnbsp;/p
h4Data and Images/h4
/td
td valign=top
h4Description/h4
pThe CD71 (HI166) Antibody recognizes a 95 kDa disulfide-bonded homodimeric type-II transmembrane glycoprotein called transferring receptor (TfR). CD71 antigen is expressed typically at high level on all proliferating cell, activated cells and erythroblasts or reticulocytes that require iron, but not on resting peripheral blood leucocytes and mature erythrocytes. CD71 antigen is also expressed at high level on cells of most neoplastic cell lines and 29-32% of bone marrow cells. A soluble form of CD71 in serum (plasma) exists besides a membrane form. Monitoring the soluble form of CD71 antigen in plasma is a diagnostic marker of anemia besides assaying plasma ferritin. The CD71 (HI160) antibody inhibits CD71/Transferrin receptor activity./p
br style=clear: both /
br style=clear: both /
h4Product Citations/h4
pnbsp;/p
h4Recommended Products/h4
pbr /
nbsp;/p
h4Alternate Names/h4
pTransferrin receptor protein 1; TfR1; TR; TfR; Trfr; T9; p90; CD71 antigen; TFRC/p
h4Accession No./h4
pa class=accession-link target=_blank href=http://www.expasy.org/uniprot/P02786P02786/abr /
a class=accession-link target=_blank href=http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=proteinamp;id=189458817NP_003225/abr /
nbsp;/p
h4Clonality/h4
pHI166/p
h4Antigen/h4
pnbsp;/p
h4Application Notes/h4
pnbsp;/p
pPurified antibody is suitable for immunohistochemistry with acetone-fixed frozen sections./p
pE: 1:500-1:1,000/p
pFACS: 1:200-1:1,000/p
pIHC: 1:200-1:500/p
pB:Use at an assay dependent concentration/p
pstrongReacts with/strongnbsp; :H/p
pnbsp;/p
h4Storage/h4
pStore at -20deg;C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment./p
/td
/tr
/tbody
/table
/div
/div
/div