CD68 Antibody

h1 class=titleCD68 Antibody/h1
div id=node-1915 class=node ntype-antibodiesRabbit Polyclonal, FITC-conjugated
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h4Catalog Number/h4
pstrong252271/strong/p
h4Unit/h4
pstrong0.1 mg /strong/p
h4Isotype/h4
Rabbit Ig
h4Applications/h4
IF
h4Species reactivity/h4
M, R
h4Format/h4
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pEach vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography./p
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h4Description/h4
pThe CD68 antigen is involved in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 binds to tissue- and organ-specific lectins and selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane helps macrophages to move over selectin-bearing substrates and other cells. CD68 is highly expressed by blood monocytes and tissue macrophages as well as many tumor cell lines promoting binding to selectins on vascular endothelium facilitating dissemination to secondary sites./p
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h4Alternate Names/h4
pMacrosialin; Gp110; CD68/p
h4Accession No./h4
pa class=accession-link href=http://www.expasy.ch/uniprot/P31996 target=_blankP31996/abr /
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h4Antigen/h4
pnbsp;/p
pKLH-conjugated synthetic peptide encompassing a sequence within the N-term region of mouse CD68./p
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h4Application Notes/h4
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pIF: 1:20-1:100/p
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h4Storage/h4
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pStore at 4deg;C. Product is guaranteed 6 months from the date of shipment./p
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